CRMP3 (DPYSL4) Rabbit Polyclonal Antibody

SKU TA322499

Anti-DPYSL4 Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-1000; WB positive control: Human fetal brain tissue; IHC: 25-100; Positive control: Human cervical cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 507-522 amino acids of Human dihydropyrimidinase-like 4
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 62 kDa
• Gene Name: dihydropyrimidinase like 4
• Database Link:
  NP_006417
  O14531
• Background: Collapsin response mediator protein 3 is an enzyme that in humans is encoded by the CRMP3 gene.It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.And plays a role in axon guidance; neuronal growth cone collapse and cell migration.Homotetramer; and heterotetramer with CRMP1; DPYSL2; DPYSL3 or DPYSL5. Interacts with PLEXA1. Phosphorylated upon DNA damage; probably by ATM or ATR.
• Synonyms: CRMP3; DRP-4; ULIP4

Reference Data