KCNH3 Rabbit Polyclonal Antibody

SKU TA322410

Anti-KCNH3 Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 10-50; Positive control: Human brain; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 95-144 amino acids of Human potassium voltage-gated channel, subfamily H (eag-related), member 3
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: potassium voltage-gated channel subfamily H member 3
• Database Link:
  NP_036416
  Q9ULD8
• Background: Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit. Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly. The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Detected only in brain; in particular in the telencephalon. Detected in the cerebral cortex; occipital pole; frontal and temporal lobe; putamen; amygdala; hippocampus and caudate nucleus.
• Synonyms: BEC1; ELK2; Kv12.2

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane