Agrin (AGRN) Rabbit Polyclonal Antibody

SKU TA321971

Anti-AGRN Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 25-100; Positive control: Human esophagus cancer; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 74-84 amino acids of human agrin
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: agrin
• Database Link:
  NP_940978
  O00468
• Background: This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ); as identified in mouse knock-out studies. The encoded protein contains several laminin G; Kazal type serine protease inhibitor; and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles; a mutation in this gene was found.
• Synonyms: CMS8; CMSPPD

Reference Data

• Protein Pathways: ECM-receptor interaction