Dysbindin (DTNBP1) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC |
---|---|
Recommended Dilution | IHC: 20-100 Positive control: Human brain Predicted cell location: Cytoplasm |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 347-351 amino acids of Human dystrobrevin binding protein 1 |
Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | dystrobrevin binding protein 1 |
Database Link | |
Background | This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes; platelet dense granules; and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1); and binds to alpha- and beta-dystrobrevins; which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
Synonyms | BLOC1S8; DBND; HPS7; My031; SDY |
Reference Data | |
Protein Families | Druggable Genome |
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