TWEAKR (TNFRSF12A) Rabbit Polyclonal Antibody

SKU TA321855

Anti-TNFRSF12A Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA: 1:1000-2000, WB: 1:200-1000, IHC: 1:5-20
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 28-129 amino acids of human tumor necrosis factor receptor superfamily, member 12A
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 14 kDa
• Gene Name: tumor necrosis factor receptor superfamily member 12A
• Database Link:
  NP_057723
  Q9NP84
• Background: Tumor necrosis factor receptor superfamily member 12A?also known as the?Tweak-receptor?(TweakR) is aprotein?that in humans is encoded by the?TNFRSF12A?gene. Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. Highly expressed in heart; placenta and kidney. Intermediate expression in lung; skeletal muscle and pancreas.
• Synonyms: CD266; FN14; TWEAKR

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction