Tryptophan Hydroxylase (TPH1) Rabbit Polyclonal Antibody

SKU TA321630

Anti-TPH1 Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 15-50; Positive control: Human thyroid cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from C terminal 250 amino acids of human tryptophan hydroxylase 1
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: tryptophan hydroxylase 1
• Database Link:
  NP_004170
  P17752
• Background: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin; an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders; including schizophrenia; somatic anxiety; anger-related traits; bipolar disorder; suicidal behavior; addictions; and others.
• Synonyms: TPRH; TRPH

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Tryptophan metabolism