Claudin 4 (CLDN4) Rabbit Polyclonal Antibody

SKU TA321325

Anti-CLDN4 Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 1000-3000; WB positive control: HT-29 cells; IHC: 25-100; Positive control: Human breast cancer; Predicted cell location: Cytoplasm, Cell membrane
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 193-209 amino acids of Human claudin 4
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 22 kDa
• Gene Name: claudin 4
• Database Link:
  NP_001296
  O14493
• Background: Claudin 4; also known as CLDN4; is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins. This gene encodes an integral membrane protein; which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome; a neurodevelopmental disorder affecting multiple systems.
• Synonyms: CPE-R; CPER; CPETR; CPETR1; hCPE-R; WBSCR8

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction