TNF alpha(TNF) Mouse Monoclonal Antibody [Clone ID: MAb11]

CAT#: TA320489

Mouse Anti-Human TNF alpha Purified (50 ug)

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 Product Datasheet for 'TA320489'

USD 153.00


Availability*
2 Weeks

Size
    • 50 ug

Product images

Specifications

Product Data
Clone Name MAb11
Recommend Dilution Flow
Reactivity Human
Host Mouse
Clonality Monoclonal
Formulation Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Concentration 0.5-1mg/ml (lot dependent)
Purification Affinity purified
Gene Name tumor necrosis factor
Background The MAb11 antibody reacts with human tumor necrosis factor-alpha (TNF alpha), a 17 kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TN alpha has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF alpha forms dimers and trimers and also exists as a 26 kDa membrane bound form. The MAb11 antibody is a neutralizing antibody.
Synonyms DIF|TNF-alpha|TNFA|TNFSF2|TNLG1F
Reference Data
Protein Families Secreted Protein, Transmembrane, Transcription Factors, Druggable Genome
Protein Pathways MAPK signaling pathway, Cytokine-cytokine receptor interaction, Apoptosis, TGF-beta signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Asthma, Systemic lupus erythematosus, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.