TLR2 Mouse Monoclonal Antibody [Clone ID: T2.5]

CAT#: TA320479

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Mouse Anti-Human/Mouse CD282 (TLR2) Purified (25 ug)



USD 185.00


Availability*
5 Days

Size
    • 25 ug


Product images

Specifications

Product Data
Clone Name T2.5
Applications FC
Recommended Dilution Flow, IHC, Functional Assay, IP
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Formulation Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration lot specific
Purification Affinity purified
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name toll like receptor 2
Background The T2.5 monoclonal antibody reacts with mouse and human Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens. T2.5 is an antagonistic antibody.
Synonyms CD282; TIL4
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Toll-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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