CCR5 Mouse Monoclonal Antibody [Clone ID: eBioT21/8 (T21/8)]

CAT#: TA320230

Mouse Anti-Human CD195 (CCR5) Purified (25 ug)


 Product Datasheet for 'TA320230'

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USD 165.00


Availability*
5 Days

Size
    • 25 ug

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Specifications

Product Data
Clone Name eBioT21/8 (T21/8)
Applications FC
Recommend Dilution Flow, ELISA, IHC, IP, WB
Reactivity Human
Host Mouse
Clonality Monoclonal
Formulation Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5-1mg/ml (lot dependent)
Purification Affinity purified
Gene Name C-C motif chemokine receptor 5 (gene/pseudogene)
Background The eBioT21/8 monoclonal antibody reacts with the amino terminus of human CCR5 (CD195), an approximately 45 kDa member of the G protein-coupled receptor (GPCR) superfamily that binds chemokines including MIP-1α, MIP-1β and RANTES. Human CCR5 is expressed on resting T cells with a memory/effector phenotype, monocytes, macrophages and immature dendritic cells. CCR5 functions as a receptor to direct the chemotaxis of lymphocytes, and is the primary co-receptor for macrophage-tropic Human Immunodeficiency Virus Type 1 (HIV-1), which binds CCR5 through gp120. Binding of the eBioT21/8 monoclonal antibody displays donor variability and may be affected by sub-optimal staining conditions.
Synonyms CC-CKR-5|CCCKR5|CCR-5|CD195|CKR-5|CKR5|CMKBR5|IDDM22
Reference Data
Protein Families GPCR, ES Cell Differentiation/IPS, Transmembrane, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Endocytosis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.