Ribonuclease T2 (RNASET2) Rabbit Polyclonal Antibody

CAT#: TA319755

Rabbit Polyclonal RNASET2 Antibody

Product Images

Western blot analysis of RNASET2 in SW480 cell lysate with RNASET2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunocytochemistry of RNASET2 in SW480 cells with RNASET2 antibody at 2.5 ug/mL.

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  Immunofluorescence of RNASET2 in SW480 cells with RNASET2 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: RNASET2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human RNASET2.
• Formulation: RNASET2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: RNASET2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ribonuclease T2
• Database Link:
  NP_003721
  Entrez Gene 292306 RatEntrez Gene 8635 Human
  UniProt ID O00584
• Background: RNASET2 Antibody: RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.
• Synonyms: bA514O12.3; RNASE6PL

Reference Data

• Protein Families: Secreted Protein