Apc1 (ANAPC1) Rabbit Polyclonal Antibody

SKU TA319499

Rabbit polyclonal APC1 phospho S355 antibody (Phospho-specific)

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1:10,000 - 1:120,000, WB: 1:200 - 1:2,000, IP: 1:100
• Reactivity: Bovine, Dog, Human, Mouse, Rat
• Modification: Phospho-specific
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 351-359 of Human Apc1 protein.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: anaphase promoting complex subunit 1
• Database Link:
  NP_073153
  Q9H1A4
• Synonyms: APC1; MCPR; TSG24
• Note: APC1 (also known as Anaphase promoting complex subunit 1, Cyclosome subunit 1, Protein Tsg24, Mitotic checkpoint regulator and ANAPC1) is 1 of at least 11 subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis