PNK (PNKP) Rabbit Polyclonal Antibody

SKU TA319448

Rabbit polyclonal anti-PNK antibody

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1:3,000 - 1:12,000, WB: 1:300 - 1:1,500
• Reactivity: Chimpanzee, Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human PNK protein.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: polynucleotide kinase 3'-phosphatase
• Database Link:
  NP_009185
  Q96T60
• Synonyms: AOA4; EIEE10; MCSZ; PNK
• Note: Mammalian PNK (also known as PNKP, Polynucleotide kinase 3'-phosphatase, DNA 5'-kinase/3'-phosphatase and Polynucleotide kinase) catalyzes the 5’ phosphorylation of nucleic acids and can have associated 3’ phosphatase activity, predictive of an important function in DNA repair following ionizing radiation or oxidative damage. PNK is a nuclear protein that is expressed in many tissues with highest expression in spleen and testis, and lowest expression in small intestine.

Reference Data

• Protein Families: Druggable Genome, Phosphatase