ZIC2 Rabbit Polyclonal Antibody

SKU TA319447

Rabbit polyclonal anti-ZIC-2 antibody

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1:10,000 - 1:50,000, WB: 1:500 - 1:2,000
• Reactivity: Chimpanzee, Dog, Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding amino acids 189-206 of Mouse ZIC-2.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: Zic family member 2
• Database Link:
  NP_009060
  O95409
• Synonyms: HPE5
• Note: ZIC2 (also known as zinc finger protein of the cerebellum 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog) is a nuclear protein that functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Hedgehog signaling pathway