Rhodopsin (RHO) Mouse Monoclonal Antibody [Clone ID: 4D2]
Product Data | |
Clone Name | 4D2 |
---|---|
Application | IF |
Recommended Dilution | ICC, IHC, IP, WB, ELISA |
Reactivity | Bovine, Human, Mouse, Porcine, Rat |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Bovine Rhodopsin |
Buffer | TBS, 50% glycerol, 0.09% sodium azide |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | rhodopsin |
Database Link | |
Background | Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq] |
Synonyms | CSNBAD1; OPN2; RP4 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
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