FTO Mouse Monoclonal Antibody [Clone ID: 5-2H10]
Product Data | |
Clone Name | 5-2H10 |
---|---|
Application | WB |
Recommended Dilution | WB: 1:1,000, IF: 1:100 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH |
Buffer | 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
Purification | Protein G purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 58 kDa |
Gene Name | fat mass and obesity associated |
Database Link | |
Background | This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq] |
Synonyms | ALKBH9; BMIQ14; GDFD |
Reference Data |
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