Collagen I (COL1A1) Rabbit Polyclonal Antibody

CAT#: TA309096

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Rabbit Anti-Collagen 1, alpha 1 propeptide Antibody



USD 513.00


Availability*
2 Weeks

Size
    • 100 ul


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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 1:1000, IHC: 1:100
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to amino acid residues specific to the collagen 1, alpha 1 propeptide conjugated to KLH
Formulation 100 ul in PBS
Purification Affinity Purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 180 kDa
Gene Name collagen type I alpha 1
Background This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]
Synonyms EDSC; OI1; OI2; OI3; OI4
Reference Data
Protein Families Druggable Genome
Protein Pathways ECM-receptor interaction, Focal adhesion
Frequently bought together (2)
Transient overexpression lysate of collagen, type I, alpha 1 (COL1A1)
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USD 436.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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USD 200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.