MAD2 (MAD2L1) Rabbit Polyclonal Antibody
Product Data | |
Application | IF, IHC, WB |
---|---|
Recommended Dilution | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000 |
Reactivity | Human (Predicted: Bovine, Mouse), Rhesus Monkey |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region within amino acids 142 and 205 of MAD2L1 (Uniprot ID#Q13257) |
Buffer | 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 24 kDa |
Gene Name | MAD2 mitotic arrest deficient-like 1 (yeast) |
Database Link | |
Background | MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq] |
Synonyms | HSMAD2; MAD2 |
Note | Seq homology of immunogen across species: Mouse (92%), Rhesus Monkey (100%), Bovine (100%) |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation |
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