HPRT (HPRT1) Rabbit Polyclonal Antibody

SKU TA308902

Rabbit Polyclonal antibody to HPRT (hypoxanthine phosphoribosyltransferase 1)

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivity: Bovine, Dog, Human (Predicted: Chicken, Pig, Rabbit, Rat, X. tropicalis), Xenopus, Zebrafish
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 23 and 218 of HPRT (Uniprot ID#P00492)
• Buffer: 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 25 kDa
• Gene Name: hypoxanthine phosphoribosyltransferase 1
• Database Link:
  NP_000185
  P00492
• Background: HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate (Keebaugh et al., 2007 [PubMed 16928426]). [supplied by OMIM]
• Synonyms: HGPRT; HPRT
• Note: Seq homology of immunogen across species: Chicken (94%), Dog (96%), Pig (97%), Rabbit (98%), Rat (96%), Xenopus laevis (92%), Zebrafish (93%), Bovine (94%), Xenopus tropicalis (92%)

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism