Meckelin (TMEM67) Rabbit Polyclonal Antibody

SKU TA308551

Rabbit polyclonal antibody to Meckelin (transmembrane protein 67)

Product Data

• Application: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivity: Bovine), Human (Predicted: Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 231 and 510 of meckelin isoform 1 (Uniprot ID#Q5HYA8)
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 112 kDa
• Gene Name: transmembrane protein 67
• Database Link:
  NP_001135773
  Q5HYA8
• Background: The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6). [provided by RefSeq]
• Synonyms: JBTS6; MECKELIN; MKS3; NPHP11; TNEM67
• Note: Seq homology of immunogen across species: Mouse (82%), Rat (81%), Bovine (88%)

Reference Data

• Protein Families: Transmembrane