MAP2K1IP1 (LAMTOR3) Rabbit Polyclonal Antibody

SKU TA308268

Rabbit Polyclonal antibody to MP1 (MAPK scaffold protein 1)

Product Data

• Application: IHC, WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivity: Bovine, Human (Predicted: Mouse, X. tropicalis)
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 124 of MP1 (Uniprot ID#Q9UHA4)
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 14 kDa
• Gene Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
• Database Link:
  NP_068805
  Q9UHA4
• Background: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein. [provided by RefSeq]
• Synonyms: MAP2K1IP1; MAPBP; MAPKSP1; MP1; PRO0633; Ragulator3
• Note: Seq homology of immunogen across species: Mouse (97%), Bovine (99%), Xenopus tropicalis (85%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: MAPK signaling pathway