Carbonic Anhydrase I (CA1) Goat Polyclonal Antibody

SKU TA305634

Goat Anti-CA1 Antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 0.03-0.1ug/ml.
• Reactivity: Human (Expected from sequence similarity: Mouse, Rat)
• Antibody Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-QAIKTKGKRAP, from the internal region of the protein sequence according to NP_001729.1.
• Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: carbonic anhydrase 1
• Database Link:
  NP_001122301
  P00915
• Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature. [provided by RefSeq]
• Synonyms: CA-I; CAB; Car1; HEL-S-11

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Nitrogen metabolism