CHRNB3 Goat Polyclonal Antibody

SKU TA303358

Goat Polyclonal Antibody against CHRNB3

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1:16,000. WB: 1-3µg/ml.
• Reactivity: Human (Expected from sequence similarity: Mouse, Rat)
• Antibody Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-SRHVKKEHFISQ, from the internal region of the protein sequence according to NP_000740.1.
• Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: cholinergic receptor nicotinic beta 3 subunit
• Database Link:
  NP_000740
  Q05901
• Background: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane
• Synonyms: acetylcholine receptor; beta-3 subunit; beta 3; beta polypeptide 3; cholinergic receptor; neuronal nicotinic; nicotinic

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane