FUCA2 Rabbit Polyclonal Antibody

SKU TA302288

Rabbit Polyclonal Antibody against FUCA2 (N-term)

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:10~50
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This FUCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human FUCA2.
• Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 54061 Da
• Gene Name: fucosidase, alpha-L- 2, plasma
• Database Link:
  NP_114409
  Q9BTY2
• Background: Alpha-L-fucosidase catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.
• Synonyms: dJ20N2.5

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Other glycan degradation