INSIG1 Rabbit Polyclonal Antibody

CAT#: TA301693

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Rabbit Polyclonal Antibody against Insig1



USD 457.00


Availability*
5 Days

Size
    • 100 ul


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Specifications

Product Data
Applications WB
Recommended Dilution WB: 2 ug/ml
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide representing an internal region of the human protein (between residues 1-100) according to Swiss-Prot# O15503.
Formulation PBS + 30% glycerol and 0.1% sodium azide
Concentration lot specific
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name insulin induced gene 1
Background Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Synonyms CL-6; CL6
Reference Data
Protein Families Druggable Genome, Transmembrane
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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