Telomerase reverse transcriptase (TERT) Mouse Monoclonal Antibody [Clone ID: 2D8]

SKU TA301587

Mouse Monoclonal Antibody against Telomerase reverse transcriptase (2D8) - Embryonic Stem Cell Marker

Product Data

• Clone Name: 2D8
• Application: FC, ICC/IF, IHC, WB
• Recommended Dilution: Knockdown Validated, Flow Cytometry: 1:50-1:200, Immunocytochemistry/ Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:1000, Immunohistochemistry: 1:50-1:100, Immunohistochemistry-Paraffin: 1:50-1:100, Immunohistochemistry-Frozen: 1:50-1:100
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Full-length recombinant hTERT from insect cells.
• Buffer: 0.1% sodium azide
• Purification: Ascites
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: telomerase reverse transcriptase
• Database Link:
  NP_937983
  O14746
• Background: Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase. Telomerase is an enzyme uniquely associated with immortal cell lines and is useful for identifying undifferentiated PSCs.
• Synonyms: CMM9; DKCA2; DKCB4; EST2; hEST2; hTRT; PFBMFT1; TCS1; TP2; TRT

Reference Data

• Protein Families: Druggable Genome