Telomerase reverse transcriptase (TERT) Mouse Monoclonal Antibody [Clone ID: 2D8]

SKU
TA301587
Mouse Monoclonal Antibody against Telomerase reverse transcriptase (2D8) - Embryonic Stem Cell Marker
  $600.00
In Stock*
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Specifications
Specifications
Product Data
Clone Name 2D8
Application FC, ICC/IF, IHC, WB
Recommended Dilution Knockdown Validated, Flow Cytometry: 1:50-1:200, Immunocytochemistry/ Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:1000, Immunohistochemistry: 1:50-1:100, Immunohistochemistry-Paraffin: 1:50-1:100, Immunohistochemistry-Frozen: 1:50-1:100
Reactivity Human
Antibody Host Mouse
Isotype IgM
Clonality Monoclonal
Immunogen Full-length recombinant hTERT from insect cells.
Buffer 0.1% sodium azide
Purification Ascites
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name telomerase reverse transcriptase
Database Link
Background Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase. Telomerase is an enzyme uniquely associated with immortal cell lines and is useful for identifying undifferentiated PSCs.
Synonyms CMM9; DKCA2; DKCB4; EST2; hEST2; hTRT; PFBMFT1; TCS1; TP2; TRT
Reference Data
Protein Categories Cancer: Brain and CNS, Cancer: Gastrointestinal, Cancer: Haematopoietic and Lymphoid, Cancer: Skin, Cardiovascular diseases, Membrane Proteins
Protein Families Druggable Genome
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