Aromatase (CYP19A1) Rabbit Polyclonal Antibody
Product Data | |
Application | ICC/IF, IHC, Simple Western, WB |
---|---|
Recommended Dilution | Immunocytochemistry/ Immunofluorescence: 1:100, Western Blot: 1 ug/ml, Immunohistochemistry: 1:200, Simple Western, Immunohistochemistry-Paraffin: 1:200 |
Reactivity | Human, Monkey |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthetic peptide made to a C-terminal portion of the human aromatase protein sequence (between residues 400-502). |
Buffer | Tris-citrate / phosphate [pH 7-8] and 0.1% sodium azide |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | cytochrome P450 family 19 subfamily A member 1 |
Database Link | |
Background | Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, fertility, and carcinogenesis. Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function. |
Synonyms | ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM |
Reference Data | |
Protein Families | Druggable Genome, P450 |
Protein Pathways | Androgen and estrogen metabolism, Metabolic pathways |
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