HA Goat Polyclonal Antibody

SKU TA160077

Goat Polyclonal Anti-Avian Influenza Hemagglutinin 3 Antibody

Product Data

• Application: ELISA, WB
• Recommended Dilution: ELISA: 1 ug/mL; WB: 1 ug/mL; WB: 2 µg/mL. <br>Avian Influenza Hemagglutinin antibody can be used for the detection of the Hemagglutinin protein from the H5N1 strain of avian influenza A in ELISA and WB. It will detect 10 ng of free peptide at 1 µg/mL. All other applications and species not yet tested.
• Reactivity: Influenza A Virus
• Antibody Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Avian Influenza Hemagglutinin 3 antibody was raised against a synthetic peptide corresponding to 14 amino acids near the center of the Hemagglutinin protein Efforts were made to use relatively conserved regions of the viral sequence as the antigen.
• Buffer: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Background: Avian Influenza Hemagglutinin 3 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.

Reference Data