IRF5 (176-240) Mouse Monoclonal Antibody [Clone ID: 10T1]
| Product Data | |
| Clone Name | 10T1 |
|---|---|
| Application | ELISA, FC, IF, IHC, IP, WB |
| Recommended Dilution | ELISA. Western blot: 1/500-1/1,000. Immunoprecipitation. Immunohistochemistry on paraffin sections: 1/50. Immunocytochemistry / Immunoflourescence. Flow cytometry. |
| Reactivity | Human, Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human IRF-5 (176-240 aa) purified from E. coli |
| Specificity | The antibody recognizes Interferon Regulatory Factor 5 (IRF-5) at aa 176-240. |
| Buffer | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified IgG fraction |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | interferon regulatory factor 5 |
| Database Link | |
| Background | IRF-5 is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs(IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines. |
| Synonyms | Interferon regulatory factor 5, IRF-5 |
| Reference Data | |
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