PPM1A Mouse Monoclonal Antibody [Clone ID: P6C7]

SKU SM6005S

PPM1A mouse monoclonal antibody, clone P6C7, Purified

Product Data

• Clone Name: P6C7
• Application: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.; Western blot: 1/250~1/1000 (1/250 as starting dilution). ; Immunofluorescence/Immnunocytochemistry. ; Immunohistochemistry on Paraffin Sections: 15 µg/ml.
• Reactivity: Human, Mouse
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant Human PP2C-alpha protein
• Specificity: This antibody detects Protein Phosphatase 2C alpha (PP2C alpha).
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein-G affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: protein phosphatase, Mg2+/Mn2+ dependent 1A
• Database Link:
  P35813
• Background: Protein phosphatase 2C(PP2Cα) is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.
• Synonyms: PPPM1A, Protein phosphatase 2C isoform alpha, PP2C-alpha, Protein phosphatase IA

Reference Data