CD44 Mouse Monoclonal Antibody [Clone ID: CVS18]

CAT#: SM502F

CD44 mouse monoclonal antibody, clone CVS18, FITC, Purified

Product Images

Staining of equine peripheral blood lymphocytes with CD44 antibody clone CVS18.

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  Staining of equine peripheral blood lymphocytes with CD44 antibody clone CVS18.

Specifications

Product Data

• Clone Name: CVS18
• Applications: FC
• Recommended Dilution: Flow cytometry: Neat - 1/10, use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.
• Reactivities: Equine
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Equine leucocytes
• Specificity: Clone CVS18 antibody detects equine CD44 and may be used as a pan equine leucocyte marker.
• Formulation: 0.09% Sodium azide and 1% BSA
  Label: FITC
  State: Purified
  State: Liquid purified IgG
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  This product is photosensitive and should be protected from light.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID Q05078
• Background: CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
• Synonyms: LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1