CD147 (BSG) Mouse Monoclonal Antibody [Clone ID: MEM-M6/1]

CAT#: SM1602PS

CD147 (BSG) mouse monoclonal antibody, clone MEM-M6/1, Purified

Size: 100 ug 200 ug


USD 257.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name MEM-M6/1
Applications FC, IHC, IP, WB
Recommended Dilution Flow Cytometry: 10 μg/ml.
Immunoprecipitation.
Western blot (under non-reducing conditions): 1 µg/ml.
Immunohistochemistry on Paraffin Sections: 10 μg/ml.
Positive tissue: testis.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of Human IgG1 (CD147Rg is secreted by transfectants as a dimer)
Specificity The antibody recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes.
The antibody MEM-M6/1 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
Formulation PBS, pH~7.4
State: Purified
State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
Preservative: 15 mM Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Background CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
Synonyms Basigin, BSG, EMMPRIN, TCSF
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.