T Cell Receptor (TCR) alpha/beta (alpha chain) Mouse Monoclonal Antibody [Clone ID: 3A8]
SKU
SM1230PS
T Cell Receptor (TCR) alpha/beta (alpha chain) mouse monoclonal antibody, clone 3A8, Purified
Product Data | |
Clone Name | 3A8 |
---|---|
Application | IHC, IP |
Recommended Dilution | Immunoprecipitation. Immunohistochemistry on Frozen Sections. Not suitable for Flow Cytometry. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Specificity | This antibody reacts with the alpha chain constant region found on all alpha beta TCR bearing T-lymphocytes. It reacts with 92-98% of all CD3+ peripheral blood lymphocytes. Negative Species: Mouse, Rat. |
Buffer | PBS State: Purified State: Liquid purified IgG fraction Stabilizer: 0.5% BSA Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Database Link | |
Background | TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR. |
Synonyms | TCRA, TCRB, T-Cell Receptor alpha, T-Cell Receptor beta, T-Cell Receptor alpha beta |
Reference Data |
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