CD59 Mouse Monoclonal Antibody [Clone ID: MEM-43]

SKU SM1145PS

CD59 mouse monoclonal antibody, clone MEM-43, Purified

Product Data

• Clone Name: MEM-43
• Application: FC, IHC, IP
• Recommended Dilution: Flow cytometry: Recommended dilution: 0.5-4 μg/ml. ; Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/ml; positive tissue: placenta.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Thymocytes and T lymphocytes.
• Specificity: The antibody reacts with well defined epitope (W40, R-53) on CD59 (Protectin), an 18-20 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed on all hematopoietic cells; it is widely present on cells in all tissues.
• Buffer: PBS, pH~7.4; State: Purified; State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE); Preservative: 15mM Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: CD59 molecule
• Database Link:
  P13987
• Background: CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.
• Synonyms: MAC-inhibitory protein, Protectin, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MSK21, MACIF, MAC-IP, MIRL, HRF20, HRF-20

Reference Data