CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: LNK16]
Product Data | |
Clone Name | LNK16 |
---|---|
Application | FC, IP |
Recommended Dilution | Flow Cytometry: Use 10 µl of 1/10-1/20 diluted antibody to label 10e6 cells or 100 µl human whole blood. Immunoprecipitation. Does not work in Immunohistochemistry on Frozen and Paraffin Sections. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Normal Human peripheral blood granulocytes. |
Specificity | This antibody recognizes CD16. This antibody has been reported to block the binding of IgG to the CD16 molecule. (4) |
Buffer | PBS, pH 7.4 State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Ion Exchange Chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | Fc fragment of IgG receptor IIIa |
Database Link | |
Background | CD16 is a 50-65kD cell surface molecule which exists in two forms, a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. |
Synonyms | FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2 |
Reference Data |
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