MSH2 Mouse Monoclonal Antibody [Clone ID: OTI10F7]
CAT#: CF814210
Carrier-free (BSA/glycerol-free) MSH2 mouse monoclonal antibody, clone OTI10F7
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI10F7 |
Applications | IHC |
Recommended Dilution | IHC 1:30 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-304 of human MSH2 (NP_000242) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 104.7 kDa |
Gene Name | Homo sapiens mutS homolog 2 (MSH2), transcript variant 1, mRNA. |
Database Link | |
Background | This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
Synonyms | COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2 |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Protein Pathways | Colorectal cancer, Mismatch repair, Pathways in cancer |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA814210 | MSH2 mouse monoclonal antibody, clone OTI10F7 |
USD 447.00 |
|
TA814210AM | MSH2 mouse monoclonal antibody, clone OTI10F7, Biotinylated |
USD 509.00 |
|
TA814210BM | MSH2 mouse monoclonal antibody, clone OTI10F7, HRP conjugated |
USD 509.00 |
|
TA814210S | MSH2 mouse monoclonal antibody, clone OTI10F7 |
USD 200.00 |
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