CTLA4 Mouse Monoclonal Antibody [Clone ID: OTI8F1]
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI8F1 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:500 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CTLA4 (NP_001032720) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 15 kDa |
| Gene Name | cytotoxic T-lymphocyte associated protein 4 |
| Database Link | |
| Background | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. provided by RefSeq, Jul 2008 |
| Synonyms | ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12 |
| Reference Data | |
| Protein Categories | ADC Targets, Allergies and autoimmune diseases, CD Markers, Diabetes, Intracellular Proteins, Membrane Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Autoimmune thyroid disease, Cell adhesion molecules (CAMs), T cell receptor signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI8F1" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA810204 | CTLA4 mouse monoclonal antibody,clone OTI8F1 | 100 ul |
$447.00
|
|
| TA810204AM | CTLA4 mouse monoclonal antibody,clone OTI8F1, Biotinylated | 100 ul |
$509.00
|
|
| TA810204BM | CTLA4 mouse monoclonal antibody,clone OTI8F1, HRP conjugated | 100 ul |
$509.00
|
|
| TA810204S | CTLA4 mouse monoclonal antibody,clone OTI8F1 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.