RAB23 Mouse Monoclonal Antibody [Clone ID: OTI1A3]

SKU CF809382

Carrier-free (BSA/glycerol-free) RAB23 mouse monoclonal antibody,clone OTI1A3

Product Data

• Clone Name: OTI1A3
• Application: IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:2000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-234 of human RAB23(NP_899050) produced in E.coli.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 26.5 kDa
• Gene Name: RAB23, member RAS oncogene family
• Database Link:
  NP_899050
  Q9ULC3
• Background: This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
• Synonyms: HSPC137

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Hedgehog signaling pathway