XPB (ERCC3) Mouse Monoclonal Antibody [Clone ID: OTI6H8]

SKU CF809371

Carrier-free (BSA/glycerol-free) ERCC3 mouse monoclonal antibody,clone OTI6H8

Product Data

• Clone Name: OTI6H8
• Application: IHC, WB
• Recommended Dilution: WB 1:500, IHC 1:1000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 191-436 of human ERCC3 (NP_000113) produced in E.coli.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 89.1 kDa
• Gene Name: ERCC excision repair 3, TFIIH core complex helicase subunit
• Database Link:
  NP_000113
  P19447
• Background: ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription. [provided by RefSeq, Jul 2008]
• Synonyms: BTF2; GTF2H; RAD25; Ssl2; TFIIH; TTD2; XPB

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Nucleotide excision repair