Thymine DNA glycosylase (TDG) Mouse Monoclonal Antibody [Clone ID: OTI3C11]

SKU
CF808610
Carrier-free (BSA/glycerol-free) TDG mouse monoclonal antibody, clone OTI3C11 (formerly 3C11)
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$600.00
3 Days*
Specifications
Product Data
Clone Name OTI3C11
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 160-253 of human TDG(NP_003202) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 45.9 kDa
Gene Name thymine DNA glycosylase
Database Link
Background The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
Synonyms hTDG
Reference Data
Protein Families Druggable Genome
Protein Pathways Base excision repair
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SKU Description Size Price
TA808610 TDG mouse monoclonal antibody, clone OTI3C11 (formerly 3C11) 100 ul
$447.00
TA808610AM TDG mouse monoclonal antibody, clone OTI3C11 (formerly 3C11), Biotinylated 100 ul
$509.00
TA808610BM TDG mouse monoclonal antibody, clone OTI3C11 (formerly 3C11), HRP conjugated 100 ul
$509.00
TA808610S TDG mouse monoclonal antibody, clone OTI3C11 (formerly 3C11) 30 ul
$200.00

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.