ROR beta (RORB) Mouse Monoclonal Antibody [Clone ID: OTI1G1]

SKU CF806996

Carrier-free (BSA/glycerol-free) RORB mouse monoclonal antibody, clone OTI1G1 (formerly 1G1)

Product Data

• Clone Name: OTI1G1
• Application: IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:150
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-260 of human RORB(NP_008845) produced in E.coli.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 51.9 kDa
• Gene Name: RAR related orphan receptor B
• Database Link:
  NP_008845
  Q92753
• Background: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
• Synonyms: bA133M9.1; NR1F2; ROR-BETA; RZR-BETA; RZRB

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors