ROS1 Mouse Monoclonal Antibody [Clone ID: OTI1F3]

SKU CF805678

Carrier-free (BSA/glycerol-free) ROS1 mouse monoclonal antibody, clone OTI1F3 (formerly 1F3)

Product Data

• Clone Name: OTI1F3
• Application: IF, IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:5000
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 2126-2347 of human ROS1(NP_002935) produced in E.coli.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Gene Name: ROS proto-oncogene 1, receptor tyrosine kinase
• Database Link:
  NP_002935
  P08922
• Background: This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]
• Synonyms: c-ros-1; MCF3; ROS

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane