GNG7 Mouse Monoclonal Antibody [Clone ID: OTI3G1]

SKU CF804188

Carrier-free (BSA/glycerol-free) GNG7 mouse monoclonal antibody, clone OTI3G1 (formerly 3G1)

Product Data

• Clone Name: OTI3G1
• Application: WB
• Recommended Dilution: WB 1:2000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 2-65 of human GNG7(NP_443079) produced in E.coli.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 7.3 kDa
• Gene Name: G protein subunit gamma 7
• Database Link:
  NP_443079
  O60262
• Background: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum. [UniProtKB/Swiss-Prot Function]
• Synonyms: FLJ00058

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Chemokine signaling pathway