IL10RA Mouse Monoclonal Antibody [Clone ID: OTI1D10]
SKU
CF506929
Carrier-free (BSA/glycerol-free) IL10RA mouse monoclonal antibody, clone OTI1D10 (formerly 1D10)
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TrueMAB™
Antibodies made against full-length proteins as antigens.
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Product Data | |
Clone Name | OTI1D10 |
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Application | IHC, WB |
Recommended Dilution | WB 1:4000, IHC 1:150 |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human IL10RA(NP_001549) produced in HEK293T cell. |
Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Ambient |
Predicted Protein Size | 60.8 kDa |
Gene Name | interleukin 10 receptor subunit alpha |
Database Link | |
Background | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009] |
Synonyms | CD210; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
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Product Manuals |
FAQs |
SDS |
Antibody Resources |
SKU | Description | Size | Price | |
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TA506929 | IL10RA mouse monoclonal antibody, clone OTI1D10 (formerly 1D10) | 100 ul |
$447.00
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TA506929AM | IL10RA mouse monoclonal antibody,clone 1D10, Biotinylated | 100 ul |
$509.00
|
|
TA506929BM | IL10RA mouse monoclonal antibody,clone 1D10, HRP conjugated | 100 ul |
$509.00
|
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TA506929S | IL10RA mouse monoclonal antibody, clone OTI1D10 (formerly 1D10) | 30 ul |
$200.00
|
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.