MADCAM1 Mouse Monoclonal Antibody [Clone ID: OTI1A5]

SKU CF506906

Carrier-free (BSA/glycerol-free) MADCAM1 mouse monoclonal antibody, clone OTI1A5 (formerly 1A5)

Product Data

• Clone Name: OTI1A5
• Application: IF, WB
• Recommended Dilution: WB 1:4000, IF 1:100
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human MADCAM1(NP_570116) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 38.3 kDa
• Gene Name: mucosal vascular addressin cell adhesion molecule 1
• Database Link:
  NP_570116
  Q13477
• Background: The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
• Synonyms: MACAM1

Reference Data

• Protein Pathways: Cell adhesion molecules (CAMs)