CD3E Mouse Monoclonal Antibody [Clone ID: OTI3E10]

CAT#: CF506064

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Carrier-free (BSA/glycerol-free) CD3E mouse monoclonal antibody,clone OTI3E10



  View other "OTI3E10" antibodies (4)

USD 600.00


Availability*
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Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI3E10
Applications IF, IHC, WB
Recommended Dilution WB 1:200~4000, IHC 1:150, IF 1:100
Reactivities Human, Dog, Monkey
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD3E(NP_000724) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 20.7 kDa
Gene Name Homo sapiens CD3e molecule (CD3E), mRNA.
Background The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Synonyms IMD18; T3E; TCRE
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

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