HGS Mouse Monoclonal Antibody [Clone ID: OTI3H7]

SKU CF505894

Carrier-free (BSA/glycerol-free) HGS mouse monoclonal antibody, clone OTI3H7 (formerly 3H7)

Product Data

• Clone Name: OTI3H7
• Application: IF, WB
• Recommended Dilution: WB 1:4000, IF 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human HGS(NP_004703) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 86 kDa
• Gene Name: hepatocyte growth factor-regulated tyrosine kinase substrate
• Database Link:
  NP_004703
  O14964
• Background: The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]
• Synonyms: HRS

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis