FTCD Mouse Monoclonal Antibody [Clone ID: OTI8C2]

SKU CF504981

Carrier-free (BSA/glycerol-free) FTCD mouse monoclonal antibody, clone OTI8C2 (formerly 8C2)

Product Data

• Clone Name: OTI8C2
• Application: IHC, WB
• Recommended Dilution: WB 1:1000, IHC 1:150
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human FTCD(NP_006648) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 58.7 kDa
• Gene Name: formimidoyltransferase cyclodeaminase
• Database Link:
  NP_006648
  O95954
• Background: The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: LCHC1

Reference Data

• Protein Pathways: Histidine metabolism, Metabolic pathways, One carbon pool by folate