ARH (LDLRAP1) Mouse Monoclonal Antibody [Clone ID: OTI4B10]

SKU CF503846

Carrier-free (BSA/glycerol-free) LDLRAP1 mouse monoclonal antibody, clone OTI4B10 (formerly 4B10)

Product Data

• Clone Name: OTI4B10
• Application: FC, IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:150, FLOW 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human LDLRAP1(NP_056442) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 33.7 kDa
• Gene Name: low density lipoprotein receptor adaptor protein 1
• Database Link:
  NP_056442
  Q5SW96
• Background: The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. [provided by RefSeq]
• Synonyms: ARH; ARH1; ARH2; FHCB1; FHCB2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis