FDFT1 Mouse Monoclonal Antibody [Clone ID: OTI2F10]

SKU CF503470

Carrier-free (BSA/glycerol-free) FDFT1 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10)

Product Data

• Clone Name: OTI2F10
• Application: IF, IHC, WB
• Recommended Dilution: WB 1:200~500, IHC 1:150, IF 1:100
• Reactivity: Human, Monkey, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human FDFT1(NP_004453) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 47.9 kDa
• Gene Name: farnesyl-diphosphate farnesyltransferase 1
• Database Link:
  NP_004453
  P37268
• Background: This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]
• Synonyms: DGPT; ERG9; SQS; SS

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Steroid biosynthesis